Y Combinator Winter 2026 Startups: YC W26 Batch Overview

Y Combinator Winter 2026 Startups YC W26 Batch StartGround

Y Combinator has spent over two decades shaping the startup landscape. With more than $800 billion in combined market value created across its portfolio, a 6.5% unicorn rate, and a quarter of those unicorns exceeding $10 billion in valuation, it remains the gold standard for early-stage accelerators. Founders who go through YC are 45% more likely to raise a Series A compared to those who don’t.

The W26 batch continues that momentum. This cohort is one of the most AI-dense in YC history. From agentic workflows and LLM infrastructure to robotics, drug discovery, and defense — the startups below represent where the smartest founders believe the next decade of technology is heading.

Key Takeaways:

  • 64% of the batch is B2B – spanning AI infrastructure, developer tools, legal tech, and healthcare
  • Consumer startups make up just 5% – signaling founders are betting heavily on enterprise AI
  • Healthcare is surging at nearly 10% – with wearable tech and drug discovery leading the way
  • Legal tech is heating up at around 4% – fueled by the rapid unicorn success of previous YC startups
  • AI is the foundation, not a feature — the overwhelming majority of startups are AI-native from day one

Below is a complete breakdown of every startup in the batch, organized by category. Whether you’re an investor scouting deal flow, a founder looking for collaborators, or simply curious about what’s next in tech, this is your definitive reference.

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B2B — General

Velum Labs

The operating system for data quality across any stack. Velum Labs is tackling one of the most persistent headaches in modern data engineering: ensuring data integrity no matter what tools you’re running.

Category: B2B · Data Quality

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Cardboard

An agentic video editor that’s rethinking how video production works. Cardboard earned the highest-upvoted Hacker News launch in YC W26, generating significant buzz in the developer community.

Category: B2B · Video Editing

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Polymath

Automating reinforcement learning environment generation. Polymath is building tools that make it dramatically easier to create RL training environments — a critical bottleneck in AI development.

Category: B2B · AI/ML Tooling

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Mendral

An AI DevOps engineer designed to handle the operational complexity of modern software infrastructure, from deployment pipelines to monitoring and incident response.

Category: B2B · DevOps

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Jinba

Automate any enterprise workflow through chat. Jinba turns conversational interfaces into a control layer for complex business processes.

Category: B2B · Enterprise Automation

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Polymorph

Personalized notifications and attribution for consumer and self-serve applications. Polymorph helps product teams deliver the right message at the right time with better measurement.

Category: B2B · Notifications & Attribution

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Sponge

Financial infrastructure for the agent economy. As AI agents begin transacting on behalf of businesses and users, Sponge is building the payment rails to support them.

Category: B2B · FinTech Infrastructure

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Cajal

Scaling formal verification to accelerate scientific discovery. Cajal applies mathematical proof techniques to validate scientific models and hypotheses at scale.

Category: B2B · Scientific Computing

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Confluence Labs

An AI research lab focused on learning efficiency — making models smarter with less data and compute.

Category: B2B · AI Research

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Oxus

AI-powered automation for internal audit workflows. Oxus helps compliance and audit teams move faster while reducing manual effort and human error.

Category: B2B · Compliance & Audit

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Envariant

Interpretability and reasoning infrastructure for foundation models. Envariant is building tools that help teams understand what their AI models are actually doing and why.

Category: B2B · AI Infrastructure

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Lance

AI-powered hotel employees. Lance is deploying intelligent agents to handle guest services, operations, and communication for hospitality businesses.

Category: B2B · Hospitality

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Tepali

An AI-native operating system for medspas. Tepali handles scheduling, patient management, and operations for the fast-growing aesthetic medicine industry.

Category: B2B · Healthcare Operations

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CardinalAI

A platform for precision outbound sales. CardinalAI uses AI to identify, qualify, and engage prospects with highly targeted messaging.

Category: B2B · Sales

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Chasi

An AI revenue engine for the equipment industry. Chasi helps equipment dealers and manufacturers optimize pricing, sales, and customer relationships.

Category: B2B · Equipment Sales

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Fern (Formerly Ishiki Labs)

Realtime AI starting with sales. Fern provides live AI assistance during sales conversations to help reps close deals more effectively.

Category: B2B · Sales AI

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Clam

Enterprise-grade security for broad-access AI agents. As organizations deploy more autonomous AI systems, Clam ensures those agents operate within safe boundaries.

Category: B2B · AI Security

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Carson

Positioned as a more capable and more secure alternative for AI-powered computer use in enterprise settings.

Category: B2B · AI Agents

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Lucent

AI that automatically watches your session replays to detect bugs and UX issues. Lucent is a tool that every engineering and product team is likely to find valuable — it spots problems humans miss by reviewing user sessions at scale.

Category: B2B · QA & Bug Detection

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Stilta

Agentic AI for patent attorneys. Stilta automates the research-intensive, detail-heavy workflows involved in patent prosecution and IP management.

Category: B2B · Legal Tech

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Agentic Fabriq

Okta for AI agents. As companies deploy fleets of autonomous agents, Agentic Fabriq provides the identity and access management layer to keep everything secure and organized.

Category: B2B · AI Identity Management

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Booko

Dynamic pricing for businesses that sell time slots. Booko helps service-based businesses optimize revenue by adjusting pricing based on demand, availability, and other signals.

Category: B2B · Pricing Optimization

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Arzule

An AI-native revenue engine starting with B2B partnerships. Arzule helps companies discover, manage, and grow partnership-driven revenue streams.

Category: B2B · Partnerships & Revenue

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Ressl

AI transformation for the trades. Ressl is bringing modern software and automation to trade businesses like plumbing, electrical, and HVAC companies.

Category: B2B · Trades & Services

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Traverse

A data research company building reinforcement learning environments for non-deterministic work — helping AI learn to handle messy, real-world tasks.

Category: B2B · AI Training Data

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Librar Labs

Building the next generation of the intelligence layer for the physical world. Librar Labs is working on systems that help machines understand and interact with physical environments.

Category: B2B · Physical AI

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MouseCat

The AI toolkit for risk teams. MouseCat gives compliance and risk professionals the tools to identify, assess, and mitigate threats faster.

Category: B2B · Risk Management

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Avoice

The AI workspace for architects. Avoice streamlines architectural design workflows with intelligent tools purpose-built for the profession.

Category: B2B · Architecture

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Zymbly

Automates admin for aircraft technicians. Zymbly eliminates paperwork overhead in aviation maintenance, letting technicians focus on the work that matters.

Category: B2B · Aviation

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Crow

Let users control your app through chat. Crow provides a conversational layer on top of existing applications, enabling natural-language interaction with software.

Category: B2B · Conversational UI

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10x Science

The AI-native platform for next-generation protein characterization. 10x Science accelerates how researchers analyze and understand proteins — a foundational step in drug discovery and biotech.

Category: B2B · Biotech

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Revion

Intelligence for automotive operations. Revion helps dealerships and automotive businesses run more efficiently with AI-driven operational insights.

Category: B2B · Automotive

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Veriad

An AI compliance officer that monitors regulatory requirements and helps organizations stay compliant without the overhead of large legal teams.

Category: B2B · Compliance

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Vela

The AI scheduling assistant that truly knows you. Vela goes beyond basic calendar management to understand your preferences, priorities, and patterns.

Category: B2B · Scheduling

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Aemon

The AI R&D engineer. Aemon helps research and development teams accelerate their work by automating experiment design, analysis, and iteration.

Category: B2B · R&D Automation

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Overshoot

Enabling developers to build and run AI vision applications. Overshoot provides the infrastructure and tools needed to deploy computer vision at scale.

Category: B2B · Computer Vision

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VOYGR

Real-world place intelligence for AI apps and agents. VOYGR provides location-aware data that helps AI systems understand and reason about physical spaces.

Category: B2B · Location Intelligence

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Rhizome AI

Always know what the FDA thinks. Rhizome AI tracks and interprets FDA regulatory signals so pharmaceutical and biotech companies can stay ahead of compliance requirements.

Category: B2B · Regulatory Intelligence

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Byteport

Global upload acceleration for files ranging from 1GB to 100TB. Byteport solves the massive pain point of moving very large files across the internet quickly and reliably.

Category: B2B · File Transfer

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RamAIn

Super fast computer-use agents to build AI employees. RamAIn focuses on speed and reliability for agents that interact with software the way humans do.

Category: B2B · AI Agents

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Perfectly

The AI-native recruiting operating system. Perfectly reimagines the entire hiring pipeline — from sourcing to offer — with AI at its core.

Category: B2B · Recruiting

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Samora AI

Multilingual voice agents with safe human escalation when needed. Samora AI serves global businesses that need voice support across languages without sacrificing quality.

Category: B2B · Voice AI

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2.

B2B — Engineering

Inviscid

Real-time building simulations to optimize energy and operational performance. Inviscid brings physics-based modeling to building management so facilities can cut costs and improve sustainability.

Category: B2B Engineering · Building Simulation

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Sentrial

Production monitoring for AI products. Sentrial provides the observability layer that AI teams need to understand how their models perform in the real world.

Category: B2B Engineering · AI Monitoring

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21st Dev

An orchestration layer for coding agents. 21st Dev coordinates multiple AI coding agents to work together on complex software projects.

Category: B2B Engineering · Developer Tools

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Shortkit

Making enterprise-scale short-form video production simple. Shortkit takes the complexity out of creating, managing, and distributing short-form video content at scale.

Category: B2B Engineering · Video Production

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Bubble Lab

Your ops super-employee in Slack. Bubble Lab embeds AI-powered operations management directly into the communication tool teams already use every day.

Category: B2B Engineering · Ops Automation

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Corelayer

An AI on-call engineer that debugs using data. Corelayer responds to production incidents by analyzing logs, metrics, and traces to find root causes fast.

Category: B2B Engineering · Incident Response

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Synthetic Sciences

AI co-scientists that run research end-to-end. Synthetic Sciences automates the full research cycle — from hypothesis generation to experiment execution to analysis.

Category: B2B Engineering · AI Research

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REV1

Shortening hardware design cycles by automating post-CAD work. REV1 tackles the tedious downstream steps that slow down the path from design to production.

Category: B2B Engineering · Hardware Design

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Valgo

Algorithmic safety validation tools for autonomy. Valgo provides the testing and certification infrastructure that autonomous systems need to prove they’re safe.

Category: B2B Engineering · Safety Validation

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Aurorin CAD

Helping hardware companies ship faster with smarter CAD workflows and automation that cuts design iteration time.

Category: B2B Engineering · CAD

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Sonarly

An AI engineer to triage and fix your production alerts. Sonarly turns noisy alerting systems into actionable responses with automated remediation.

Category: B2B Engineering · Alert Management

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Martini

Collaborative AI-native filmmaking for professionals. Martini gives film production teams intelligent tools for planning, editing, and coordinating complex shoots.

Category: B2B Engineering · Filmmaking

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Sparkles

Make everyone on your team an engineer. Sparkles lowers the barrier to building software so non-technical team members can contribute to development.

Category: B2B Engineering · No-Code/Low-Code

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Canary

The first AI QA engineer that understands your codebase. Canary reads and comprehends your code to write and maintain tests that actually matter.

Category: B2B Engineering · QA & Testing

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Visibl Semiconductors

AI agents for chip design. Visibl is applying artificial intelligence to the notoriously complex and resource-intensive process of semiconductor design.

Category: B2B Engineering · Chip Design

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Crosslayer Labs

Protect, monitor, and defend your internet presence. Crosslayer Labs offers a comprehensive security suite for managing and safeguarding online assets.

Category: B2B Engineering · Cybersecurity

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Button Computer

Button is the wearable AI that can talk. A hardware product that puts a conversational AI assistant on your body — always accessible, always listening when activated.

Category: B2B Engineering · Wearable AI

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B2B — Engineering

B2B — Infrastructure

Autumn AI

Stalk your prospects at scale. Autumn AI automates deep prospect research so sales teams can personalize outreach with rich intelligence on every target.

Category: B2B Infrastructure · Sales Intelligence

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Salus

Guardrails to validate your agent’s actions before they execute. Salus provides a safety layer that checks AI agent decisions against predefined rules before anything happens.

Category: B2B Infrastructure · AI Safety

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Maven

Payments for voice agents. Maven handles the financial transaction layer when AI voice agents need to process payments during conversations.

Category: B2B Infrastructure · Payments

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Moda

The monitoring and analytics layer your AI agents need. Moda gives teams visibility into how their agents are performing, where they’re failing, and how to improve them.

Category: B2B Infrastructure · AI Observability

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Piris Labs

Inference at light speed. Piris Labs is building ultra-fast AI inference infrastructure that dramatically reduces latency for model serving.

Category: B2B Infrastructure · AI Inference

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Chamber

Autopiloting your AI infrastructure. Chamber automates the management and optimization of the compute resources that power AI workloads.

Category: B2B Infrastructure · AI Ops

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RunAnywhere

The default way of running on-device AI at scale. RunAnywhere makes it simple to deploy and manage AI models directly on edge devices rather than in the cloud.

Category: B2B Infrastructure · Edge AI

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Cascade

Making autonomous intelligence safe and reliable. Cascade builds the guardrails and testing frameworks that make it possible to trust AI systems in production.

Category: B2B Infrastructure · AI Safety

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IncidentFox

An AI SRE agent that triages, coordinates, and fixes production incidents. IncidentFox acts as an autonomous first responder when things go wrong in your infrastructure.

Category: B2B Infrastructure · SRE

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Haladir

Building operational superintelligence. Haladir is developing AI systems designed to handle complex operational decision-making at superhuman levels.

Category: B2B Infrastructure · AI Operations

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Captain

Accurate knowledge search that scales. Captain provides an API-first unified data layer to ship enterprise RAG pipelines in minutes. Notably, Captain was the only team coached by YC CEO Garry Tan — which may signal strong conviction from leadership.

Category: B2B Infrastructure · RAG & Search

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Tensol

AI employees for your business. Tensol deploys autonomous agents that handle defined business functions with minimal human oversight.

Category: B2B Infrastructure · AI Agents

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Terminal Use

Vercel for background agents. Terminal Use provides the hosting and deployment infrastructure specifically designed for AI agents that run in the background.

Category: B2B Infrastructure · Agent Hosting

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Luel

Turning everyday words and actions into usable training data. Luel captures natural human behavior and converts it into structured datasets for model training.

Category: B2B Infrastructure · Training Data

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Shofo

Common Crawl for video. Shofo is building the large-scale video dataset infrastructure that AI researchers and companies need for training multimodal models.

Category: B2B Infrastructure · Video Data

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Oximy

The system of record for enterprise AI usage. Oximy tracks how organizations use AI across teams, tools, and models — providing visibility, governance, and cost control.

Category: B2B Infrastructure · AI Governance

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Compresr

LLM-native context compression. Compresr reduces the token footprint of prompts and context windows without losing meaning — cutting costs and improving speed.

Category: B2B Infrastructure · LLM Optimization

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Cumulus Labs

Performant serverless GPU inference. Cumulus Labs provides on-demand GPU compute for AI inference without the overhead of managing infrastructure.

Category: B2B Infrastructure · GPU Compute

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Orthogonal

Agentic payments for APIs. Orthogonal enables AI agents to autonomously discover, negotiate, and pay for API services they need.

Category: B2B Infrastructure · API Payments

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Didit

An all-in-one identity platform for fast human verification. Didit helps services distinguish real humans from bots and AI agents with minimal friction.

Category: B2B Infrastructure · Identity Verification

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Bits

Fast and safe cloud computing infrastructure, focused on making GPU workloads accessible and secure.

Category: B2B Infrastructure · Cloud Computing

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B2B — Finance & Accounting

FullSeam

An AI employee for finance and accounting teams. FullSeam automates the repetitive, detail-heavy work that dominates the day-to-day of finance professionals.

Category: B2B Finance & Accounting

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Payna

Crypto and fintech compliance simplified. Payna helps companies in the digital asset space navigate regulatory requirements without drowning in complexity.

Category: B2B Finance & Accounting


Balance

Full-stack AI accounting. Balance handles the entire accounting workflow — from bookkeeping to reporting — with AI at every step.

Category: B2B Finance & Accounting

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End Close

AI-powered reconciliation for high-volume payments companies. End Close automates the matching and verification process that payments businesses struggle with at scale.

Category: B2B Finance & Accounting

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Copperlane

AI agents for mortgage origination. Copperlane streamlines the complex, document-heavy process of originating mortgages from application to close.

Category: B2B Finance & Accounting

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Q2Q

Building tools in the finance and accounting space.

Category: B2B Finance & Accounting

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o11

The AI agent inside every app. o11 embeds intelligent automation directly into existing software applications.

Category: B2B Finance & Accounting

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B2B — Marketing

Wideframe

An AI agent for video work outside the non-linear editor. Wideframe handles the time-consuming tasks around video production that happen before and after the edit.

Category: B2B Marketing · Video

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Reframe

AI agents to automate hardware procurement. Reframe brings intelligent automation to the traditionally manual process of sourcing and purchasing hardware.

Category: B2B Marketing · Procurement

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Sitefire

Marketing suite for the agentic web. As AI agents increasingly browse and interact with the web, Sitefire helps brands optimize their presence for both human and agent audiences.

Category: B2B Marketing

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B2B — Supply Chain & Logistics

Pollinate

AI agents for the supply chain. Pollinate deploys autonomous agents that manage procurement, inventory, and logistics workflows.

Category: B2B Supply Chain & Logistics

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Burt

AI teammates for logistics. Burt works alongside logistics teams to optimize routing, scheduling, and coordination across supply chains.

Category: B2B Supply Chain & Logistics

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Asimov

An internet-scale marketplace for robot training data. Asimov connects robotics companies with the diverse, real-world data they need to train better robots.

Category: B2B Supply Chain & Logistics · Robotics Data

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B2B — Security

Lexius

AI security guards. Lexius brings intelligent monitoring and threat detection to physical security operations.

Category: B2B Security

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Hex Security

Agentic offensive security at scale. Hex Security uses autonomous agents to continuously probe and test an organization’s defenses.

Category: B2B Security

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Protent

Turning passive surveillance into proactive intelligence. Protent transforms security camera footage into actionable threat detection and prevention.

Category: B2B Security

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BeeSafe AI

Stopping scams before they reach your customers. BeeSafe AI provides fraud and scam detection that intercepts threats upstream.

Category: B2B Security

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B2B — Sales

Caretta

Realtime AI for sales calls. Caretta provides live coaching and insights during sales conversations to help reps perform at their best.

Category: B2B Sales

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B2B — Retail

Return Signals

An AI luxury concierge for e-commerce brands. Return Signals helps premium online retailers deliver personalized, white-glove customer experiences.

Category: B2B Retail

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B2B — Legal

The legal tech category is one of the fastest-growing segments in this batch, likely inspired by the rapid success of companies like Legora and Harvey, both of which reached unicorn status shortly after founding. Around 4% of the W26 batch is building in this space.

The AI-native law firm for growth-stage companies. General Legal combines legal expertise with AI to deliver fast, scalable legal services to startups and scale-ups.

Category: B2B Legal

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AutoSitu

An AI-native workspace for municipal development review. AutoSitu streamlines the permitting and planning approval process for local governments.

Category: B2B Legal · Government

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AI law firm and legal tech platform for startups. Vector Legal provides accessible, technology-driven legal services tailored to early-stage companies.

Category: B2B Legal

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Wayco

An AI operator for legal case referrals. Wayco connects clients with the right attorneys by intelligently routing and managing case referrals.

Category: B2B Legal

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Fed10

AI agents that replace your policy consultants. Fed10 automates the monitoring, analysis, and interpretation of government policy changes.

Category: B2B Legal · Policy

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LegalOS

The AI-powered law firm for complex work visas. LegalOS specializes in immigration law, using AI to navigate the notoriously complicated visa application process.

Category: B2B Legal · Immigration

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Arcline

Startup legal work handled by elite lawyers with same-day turnaround. Arcline pairs top legal talent with AI tools to deliver premium legal services at startup speed.

Category: B2B Legal

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B2B — Productivity

Sila

An agent and team communication workspace. Sila rethinks how teams and AI agents collaborate in shared digital environments.

Category: B2B Productivity

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Unisson

The AI product specialist for customer-facing teams. Unisson gives support, sales, and success teams deep product knowledge on demand.

Category: B2B Productivity

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Emdash

An open-source agentic development environment. Emdash provides developers with a workspace designed from the ground up for working alongside AI coding agents.

Category: B2B Productivity · Developer Tools

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Cofia

AI automations that write themselves. Cofia lets teams describe what they want automated in natural language, and the system builds the workflow.

Category: B2B Productivity · Automation

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Robby

Agentic revenue growth for home service businesses. Robby automates lead management, scheduling, and follow-ups for contractors and service companies.

Category: B2B Productivity · Home Services

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B2B — Operations

Corvera

AI agents for CPG brands. Corvera helps consumer packaged goods companies manage retail operations, promotions, and distribution more effectively.

Category: B2B Operations

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MochaCare

AI-supercharged humans for home care agency growth. MochaCare combines AI tools with human caregivers to help home care agencies scale operations and improve patient outcomes.

Category: B2B Operations · Home Care

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EigenPal

AI document workflows for enterprises. EigenPal automates how large organizations create, review, route, and manage documents.

Category: B2B Operations · Document Management

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Pollen

AI agents for customer success. Pollen helps CS teams proactively manage accounts, reduce churn, and drive expansion with intelligent automation.

Category: B2B Operations · Customer Success

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B2B — Analytics

Approxima

One package to take your mobile app to production. Approxima simplifies the mobile development pipeline with an integrated toolkit for deployment and analytics.

Category: B2B Analytics · Mobile

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Laurence

Reinforcement learning for performance marketing. Laurence applies RL techniques to optimize ad spend, targeting, and campaign performance in real time.

Category: B2B Analytics · Marketing

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Constellation Space

AI for space mission assurance. Constellation Space helps space agencies and companies ensure mission success through predictive analytics and intelligent monitoring.

Category: B2B Analytics · Space

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B2B — Human Resources

Ashr

Mimic users in your production environment to catch agent failures. Ashr creates synthetic user simulations to stress-test AI agents before they encounter real customers.

Category: B2B Human Resources · Testing

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Skillsync

Find anyone in open source and across companies. Skillsync is a talent discovery platform that identifies developers based on their actual code contributions and technical profiles.

Category: B2B Human Resources · Talent Discovery

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FinTech

Axis

An AI trading system for commodities markets. Axis applies machine learning to identify patterns and execute trades in the complex world of commodity trading.

Category: FinTech · Trading

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Kita

Turn documents into signals for lenders. Kita extracts and interprets financial data from documents to help lending institutions make better credit decisions.

Category: FinTech · Lending

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Unifold

Multi-chain deposit and payment infrastructure. Unifold simplifies the complexity of accepting and managing payments across multiple blockchain networks.

Category: FinTech · Crypto Payments

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Panta

A commercial insurance brokerage run by AI agents that scales like software. Panta is reimagining insurance distribution by replacing manual brokerage work with autonomous agents.

Category: FinTech · Insurance

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Fenrock AI

The most powerful AI agents for financial crime compliance. Fenrock helps financial institutions detect and prevent money laundering, fraud, and other financial crimes.

Category: FinTech · Compliance

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Sequence Markets

Smarter and faster trade execution for digital assets. Sequence Markets brings sophisticated execution algorithms to the cryptocurrency trading space.

Category: FinTech · Payments

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ZeroSettle

Avoid the 30% app store tax by supporting direct billing in your app. ZeroSettle helps mobile developers process payments outside of traditional app store channels.

Category: FinTech · Payments

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Grade

Payroll for performance. Grade ties compensation directly to measurable outcomes, creating a more transparent and incentive-aligned pay structure.

Category: FinTech · Payments

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Forum

The first regulated exchange to trade on attention. Forum creates a market where attention — the currency of the creator economy — can be measured and traded.

Category: FinTech · Payments

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Proximitty

Autonomous loan servicing and collections. Proximitty uses AI agents to handle the ongoing management and collection of loans with minimal human involvement.

Category: FinTech · Credit & Lending

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Maywood

AI for mergers and acquisitions. Maywood brings intelligent automation to the deal-making process in investment banking.

Category: FinTech · Banking & Exchange

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Verdex

Satellite imagery verification for insurance. Verdex uses satellite data to help insurers verify claims, assess risk, and underwrite policies more accurately.

Category: FinTech · Insurance

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SpotPay

Cross-border personal finance on stablecoins. SpotPay lets individuals send money, save, and manage finances across borders using stablecoin infrastructure.

Category: FinTech · Consumer Finance

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Healthcare

Healthcare makes up nearly 10% of this batch, with founders building across drug discovery, clinical operations, patient care, and regulatory tech. Wearable technologies and AI-native platforms are leading the way.

Ditto Biosciences

Evolutionary therapies for autoimmune disease. Ditto Biosciences is developing novel treatments that leverage evolutionary biology to tackle autoimmune conditions.

Category: Healthcare · Drug Discovery

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Origin

AI for safer cell and gene therapies. Origin is building tools that improve the safety and efficacy of one of medicine’s most promising frontiers.

Category: Healthcare · Cell & Gene Therapy

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CellType

The agentic drug company. CellType simulates human biology to discover and develop new drugs using AI-driven biological modeling.

Category: Healthcare · Drug Discovery

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Beacon Health

AI agents for primary care. Beacon Health deploys AI assistants that support primary care providers with diagnosis, documentation, and patient communication.

Category: Healthcare · Primary Care

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Eos Ai

The autonomous operating system for healthcare. Eos Ai provides a comprehensive AI platform that manages clinical and administrative workflows across healthcare organizations.

Category: Healthcare · Operations

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Docura Health

An AI-native medico-legal firm. Docura Health sits at the intersection of healthcare and law, using AI to handle medical-legal documentation and case management.

Category: Healthcare · Medico-Legal

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Patientdesk AI

An AI voice agent for patient calls and admin workflows. Patientdesk handles appointment scheduling, insurance verification, and routine patient communication automatically.

Category: Healthcare · Patient Communication

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Ritivel

An AI-native platform for regulatory document submission. Ritivel helps pharmaceutical and medical device companies prepare and submit regulatory filings faster and more accurately.

Category: Healthcare · Regulatory

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Overdrive

AI-powered medical billing. Overdrive automates the complex world of medical coding, claim submission, and revenue cycle management.

Category: Healthcare · Billing

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Zatanna

Adaptive healthcare admin agents. Zatanna deploys AI that learns and adapts to each healthcare organization’s unique administrative processes.

Category: Healthcare · Admin

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Ruma Care

Helping clinics get patients on biologics faster. Ruma Care streamlines the authorization and onboarding process for biologic treatments.

Category: Healthcare · Patient Access

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Strand AI

Curated multimodal datasets for biology AI. Strand AI provides the high-quality biological data that AI models need to make breakthroughs in life sciences.

Category: Healthcare · Biotech Data

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Prana

An AI primary care doctor in your pocket. Prana provides accessible, AI-driven primary care consultations directly through a mobile app.

Category: Healthcare · Telehealth

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Opalite Health

Solving language barriers in healthcare. Opalite Health provides real-time translation and interpretation tools so patients and providers can communicate effectively regardless of language.

Category: Healthcare · Language Access

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Mango Medical

Simulating orthopedic surgeries based on CT scans. Mango Medical lets surgeons plan and rehearse complex procedures digitally before operating on real patients.

Category: Healthcare · Surgical Planning

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Consumer

Consumer startups represent just 5% of this batch — a notable shift from previous YC cohorts. The few that made it in are building some of the most creative products in the group.

Fort

A strength tracking wearable. While fitness wearables have exploded in popularity for sleep, heart rate, and activity — Fort is the first focused specifically on tracking strength performance. Given the success of Garmin, Oura, and Whoop, this is a space to watch.

Category: Consumer · Electronics / Wearables

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Doomersion

Doomscroll to learn languages. Doomersion turns the addictive habit of endless scrolling into a language learning experience — meeting users where they already are.

Category: Consumer · Electronics / Education

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Pocket

The world’s best AI note-taking device and app. Pocket combines dedicated hardware with intelligent software to capture, organize, and surface your notes when you need them.

Category: Consumer · Electronics

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CatchBack Cards

A platform for maximizing the thrill of collecting trading cards. CatchBack Cards brings technology to the passionate world of card collecting.

Category: Consumer · Gaming

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Mantis Biotechnology

Physics-enhanced datasets for low-resource machine learning. Mantis uses physics-based augmentation to help ML models learn effectively from limited data.

Category: Consumer · Gaming / ML

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CodeWisp

Anyone can create real games with AI. CodeWisp democratizes game development by letting non-programmers build functional games using natural language and AI.

Category: Consumer · Gaming

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Pax Historia

The first AI-powered grand strategy sandbox game. Players create worlds, publish them to the community, and play to answer “what would have happened if…?” questions. YC CEO Garry Tan has praised it as one of the highest-usage, highest-retaining LLM games ever made.

Category: Consumer · Gaming

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Resonate

The first AI-native messaging platform. Resonate reimagines messaging from the ground up with AI capabilities woven into every conversation.

Category: Consumer · Communication

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Industrials — Manufacturing & Robotics

Servo7

Simple and rapidly deployed robots for industry work. Servo7 makes industrial robotics accessible to companies that previously couldn’t justify the complexity.

Category: Industrials · Manufacturing & Robotics

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Remy Ai

Automating dexterous tasks in warehouses. Remy Ai builds robots capable of the fine motor skills needed for picking, sorting, and handling in logistics environments.

Category: Industrials · Manufacturing & Robotics

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Human Archive

A multimodal data provider for robotics learning. Human Archive captures and packages human movement data to help robots learn physical tasks.

Category: Industrials · Manufacturing & Robotics

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OneRobot

World models for VLA evaluations and training. OneRobot builds simulated environments for testing and training vision-language-action models used in robotics.

Category: Industrials · Manufacturing & Robotics

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General Astronautics

The space robotics company. General Astronautics is developing robots designed to operate in the harsh environment of space.

Category: Industrials · Manufacturing & Robotics

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Kyten Technologies

A custom aerospace-grade battery pack factory. Kyten builds high-performance battery packs designed to meet the demanding specifications of aerospace applications.

Category: Industrials · Manufacturing & Robotics

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Origami Robotic

Manipulate-anything robots. Origami Robotic builds versatile robotic systems capable of handling a wide variety of physical objects and tasks.

Category: Industrials · Robotics

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Hlabs

Making an industrial supply chain for building robots in the USA. Hlabs is tackling the domestic manufacturing infrastructure needed to scale robotics production.

Category: Industrials · Robotics Supply Chain

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Congruent

Building radars for end-to-end autonomy. Congruent develops radar systems that enable autonomous vehicles and robots to perceive their environment with high reliability.

Category: Industrials · Autonomy

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DAIVIN

Tankless dive gear providing breath autonomy at sea, land, and space. DAIVIN is developing next-generation breathing technology for extreme environments.

Category: Industrials · Deep Tech

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ARC Prize Foundation

AI benchmarks that measure general intelligence and inspire new ideas. ARC Prize Foundation creates evaluation frameworks that push the boundaries of what AI systems can do.

Category: Industrials · AI Benchmarking

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Industrials — Aviation & Space

Galactic Resource Utilization Space

Building the first hotel on the Moon. An audacious bet on space tourism and lunar infrastructure.

Category: Industrials · Aviation & Space

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Beyond Reach Labs

Space solar arrays that grow to the size of a football field in orbit. Beyond Reach Labs is developing expandable solar technology for powering operations in space.

Category: Industrials · Aviation & Space

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AxionOrbital Space

Foundation models for 24/7 Earth observation. AxionOrbital brings AI to satellite imagery, enabling continuous monitoring and analysis of our planet.

Category: Industrials · Aviation & Space

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Industrials — Energy

Terranox AI

AI-powered uranium exploration. Terranox uses machine learning to identify promising uranium deposits more efficiently than traditional geological methods.

Category: Industrials · Energy

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Condor Energy

An energy operating system enabling reliable, cheap, and sustainable electricity supply. Condor Energy optimizes energy generation and distribution for better outcomes.

Category: Industrials · Energy

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Squid

AI-powered grid planning in your browser. Squid makes electrical grid planning accessible and fast with intelligent modeling tools.

Category: Industrials · Energy

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RoboDock

Robots that run autonomous depots for autonomous fleets. RoboDock builds the charging and maintenance infrastructure that self-driving vehicles need.

Category: Industrials · Energy / Autonomy

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Voxel Energy

Energy-independent data centers with solar and repurposed batteries. Voxel Energy is building sustainable power solutions specifically designed for the growing compute demands of AI.

Category: Industrials · Energy

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Industrials — Defense

Seeing Systems

AI drone systems for defence. Seeing Systems is developing intelligent drone platforms for military and defense applications.

Category: Industrials · Defense

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Industrials — Climate

OctaPulse

Robotics and computer vision to automate fish farming from hatchery to harvest. OctaPulse brings modern automation to aquaculture, one of the world’s fastest-growing food production sectors.

Category: Industrials · Climate / Aquaculture

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The Bottom Line

YC’s W26 batch paints a clear picture of where the startup world is heading. AI is no longer a feature — it’s the foundation. The overwhelming majority of these startups are building AI-native products from day one, not retrofitting intelligence into existing workflows.

The concentration on B2B signals that founders see the biggest near-term opportunities in selling to businesses rather than consumers. The rise of legal tech and healthcare further suggests that AI is mature enough to tackle regulated, high-stakes industries that were previously too risky for startups.

Whether any of these 180+ companies become the next Stripe, Airbnb, or DoorDash remains to be seen. But if YC’s track record is any guide, the odds are good that several from this batch will make a serious dent.


Complete List of All YC W26 Batch Startups

If you found the above listings overwhelimng, here’s a table with quick description of what they are building.

# Company Name Category What they are building Website
1 Travo Real Estate and Construction AI to collect and analyze real estate data Visit Website
2 Bidflow Real Estate and Construction AI Copilot for Electrical Estimating Visit Website
3 Scout Out Real Estate and Construction AI generated proposals for residential construction project Visit Website
4 Velum Labs B2B The OS for data quality across any stack Visit Website
5 Cardboard B2B Agentic video editor Visit Website
6 Polymath B2B Automating RL environment generation Visit Website
7 Mendral B2B AI DevOps Engineer Visit Website
8 Jinba B2B Automate any enterprise workflow through chat Visit Website
9 Polymorph B2B Personalized notifs & attribution for consumer and self-serve app Visit Website
10 Sponge B2B Financial infrastructure for the agent economy Visit Website
11 Cajal B2B Scaling formal verification to accelerate scientific discovery Visit Website
12 Confluence Labs B2B We’re an AI research lab focused on learning efficiency Visit Website
13 Oxus B2B AI-powered automation for internal audit workflows Visit Website
14 Envariant B2B Interpretability and reasoning infra for foundation models. Visit Website
15 Lance B2B Your Hotel’s Best Employees Visit Website
16 Tepali B2B AI-native operating system for medspas Visit Website
17 CardinalAI B2B Platform for Precision Outbound Visit Website
18 Chasi B2B AI Revenue Engine for the Equipment Industry Visit Website
19 Fern (Formerly Ishiki Labs) B2B Realtime AI starting with sales Visit Website
20 Clam B2B Enterprise-grade security for broad-access AI Agents like OpenClaw Visit Website
21 Carson B2B more capable than Cowork, more secure than OpenClaw Visit Website
22 Lucent B2B AI that automatically watches your session replays to detect bugs. Visit Website
23 Stilta B2B Agentic AI for patent attorneys Visit Website
24 Agentic Fabriq B2B Okta for Agents. Visit Website
25 Booko B2B Dynamic pricing for businesses that sell time slots Visit Website
26 Arzule B2B AI-native revenue engine, starting with B2B partnerships Visit Website
27 Ressl B2B AI Transformation for the Trades Visit Website
28 Traverse B2B Data research company building RL envs for non-deterministic work Visit Website
29 Librar Labs B2B The next generation of the intelligence layer for the physical worl Visit Website
30 MouseCat B2B The AI Toolkit for Risk Teams Visit Website
31 Avoice B2B The AI Workspace For Architects Visit Website
32 Zymbly B2B Automates admin for aircraft technicians Visit Website
33 Crow B2B Let users control your app through chat Visit Website
34 10x Science B2B The AI-native platform for next-generation protein characterization. Visit Website
35 Revion B2B Intelligence for Automotive Operations Visit Website
36 Veriad B2B AI compliance officer Visit Website
37 Vela B2B The AI Scheduling Assistant that truly knows you. Visit Website
38 Aemon B2B The AI R&D Engineer Visit Website
39 Overshoot B2B Enable developers to build and run AI vision applications Visit Website
40 VOYGR B2B Real-world place intelligence for AI apps and agent Visit Website
41 Rhizome AI B2B Always know what the FDA thinks Visit Website
42 Byteport B2B Global upload acceleration for 1GB-100TB files. Visit Website
43 RamAIn B2B Super fast computer-use agents to build AI employees. Visit Website
44 Perfectly B2B The AI-native Recruiting Operating System Visit Website
45 Samora AI B2B Multilingual voice agents with safe human escalation when needed Visit Website
46 Inviscid B2B Engineering Real-time Building Simulations to Optimize Energy and Operational… Visit Website
47 Sentrial B2B Engineering Production Monitoring for AI Products Visit Website
48 21st Dev B2B Engineering Orchestration layer for coding agents Visit Website
49 Shortkit B2B Engineering We make enterprise-scale short-form video really simple. Visit Website
50 Bubble Lab B2B Engineering Your ops super-employee in Slack Visit Website
51 Corelayer B2B Engineering AI on-call engineer that debugs using data Visit Website
52 Synthetic Sciences B2B Engineering AI co-scientists that run research end-to-end Visit Website
53 REV1 B2B Engineering Shortening hardware design cycles by automating post-CAD work Visit Website
54 Valgo B2B Engineering Algorithmic safety validation tools for autonomy Visit Website
55 Aurorin CAD B2B Engineering We help hardware companies ship faster Visit Website
56 Sonarly B2B Engineering AI engineer to triage and fix your production alerts Visit Website
57 Martini B2B Engineering Collaborative AI-native filmmaking for professionals Visit Website
58 Sparkles B2B Engineering Make everyone on your team an engineer Visit Website
59 Canary B2B Engineering The first AI QA engineer that understands your codebas Visit Website
60 Visibl Semiconductors B2B Engineering AI agents for chip design. Visit Website
61 Crosslayer Labs B2B Engineering Protect, monitor and defend your Internet presence Visit Website
62 Button Computer B2B Engineering Button is the wearable AI that can talk. Visit Website
63 Autumn AI B2B Infrastructure Stalk your prospects at scale. Visit Website
64 Salus B2B Infrastructure Guardrails to validate your agent’s actions before they execute Visit Website
65 Maven B2B Infrastructure Payments for Voice Agents Visit Website
66 Moda B2B Infrastructure The monitoring & analytics layer your AI agents need Visit Website
67 Piris Labs B2B Infrastructure Inference at Light Speed Visit Website
68 Chamber B2B Infrastructure Autopiloting your AI infrastructure Visit Website
69 RunAnywhere B2B Infrastructure The default way of running On-Device AI at Scale Visit Website
70 Cascade B2B Infrastructure Making Autonomous Intelligence Safe & Reliable Visit Website
71 IncidentFox B2B Infrastructure AI SRE agent that triages, coordinates, and fixes production incidents Visit Website
72 Haladir B2B Infrastructure Building Operational Superintelligence. Visit Website
73 Captain B2B Infrastructure Accurate knowledge search that scales Visit Website
74 Tensol B2B Infrastructure AI Employees for your Business, Powered by OpenClaw Visit Website
75 Terminal Use B2B Infrastructure Vercel for background agents Visit Website
76 Luel B2B Infrastructure Turning everyday words and actions into usable training data. Visit Website
77 Shofo B2B Infrastructure Common Crawl for Video Visit Website
78 Oximy B2B Infrastructure The system of record for enterprise AI usage. Visit Website
79 Compresr B2B Infrastructure LLM-native context compression Visit Website
80 Cumulus Labs B2B Infrastructure Performant serverless GPU inference Visit Website
81 Orthogonal B2B Infrastructure Agentic Payments for APIs Visit Website
82 Didit B2B Infrastructure All-in-one identity platform for fast human verification. Visit Website
83 Bits B2B Infrastructure Fast and Safe OpenClaw on the cloud Visit Website
84 Axis FinTech An AI Trading System for Commodities Markets Visit Website
85 Kita FinTech Turn documents into signals for lenders Visit Website
86 Unifold FinTech Multi-chain deposit and payment infrastructure Visit Website
87 Panta FinTech Commercial insurance brokerage run by AI agents. Scales like softw… Visit Website
88 Fenrock AI FinTech The most powerful AI agents for Financial Crime Compliance Visit Website
89 Pollinate B2B Supply Chain & Logistics AI Agents for the supply chain. Visit Website
90 Burt B2B Supply Chain & Logistics AI teammates for logistics Visit Website
91 Asimov B2B Supply Chain & Logistics Internet-scale marketplace for robot training data Visit Website
92 Ditto Biosciences Healthcare Evolutionary therapies for autoimmune disease Visit Website
93 Origin Healthcare AI for safer cell & gene therapies Visit Website
94 CellType Healthcare The agentic drug company. We simulate human biology. Visit Website
95 Beacon Health Healthcare AI Agents for Primary Care Visit Website
96 Eos Ai Healthcare The autonomous operating system for healthcare Visit Website
97 Docura Health Healthcare AI-Native Medico-Legal Firm Visit Website
98 Patientdesk AI Healthcare AI voice agent for patient calls & admin workflows Visit Website
99 Ritivel Healthcare AI-native platform for regulatory document submissio Visit Website
100 Overdrive Healthcare AI Powered Medical Billing Visit Website
101 Zatanna Healthcare Adaptive Healthcare Admin Agents Visit Website
102 Ruma Care Healthcare We help clinics get patients on biologics faster Visit Website
103 Strand AI Healthcare Curated multimodal datasets for biology AI Visit Website
104 Prana Healthcare An AI primary care doctor in your pocket Visit Website
105 Opalite Health Healthcare Solving language barriers in healthcare Visit Website
106 Mango Medical Healthcare We simulate orthopedic surgeries based on CT scans Visit Website
107 Seeing Systems Industrials Defense AI Drone Systems for Defence Visit Website
108 Servo7 Industrials Manufacturing and Robotics Simple and rapidly deployed robots for industry work Visit Website
109 Remy Ai Industrials Manufacturing and Robotics Automating dexterous tasks in warehouses Visit Website
110 Human Archive Industrials Manufacturing and Robotics Multimodal data provider for robotics learning Visit Website
111 OneRobot Industrials Manufacturing and Robotics World models for VLA evals and training. Visit Website
112 General Astronautics Industrials Manufacturing and Robotics The Space Robotics Company Visit Website
113 Kyten Technologies Industrials Manufacturing and Robotics Custom aerospace-grade battery pack factory Visit Website
114 FullSeam B2B Finance & Accounting FullSeam is an AI employee for finance and accounting teams. Visit Website
115 Payna B2B Finance & Accounting Crypto/fintech compliance simplified. N/A
116 Balance B2B Finance & Accounting Full-Stack AI Accounting Visit Website
117 End Close B2B Finance & Accounting AI powered reconciliation for high-volume payments companies Visit Website
118 Copperlane B2B Finance & Accounting Agents for Mortgage Origination Visit Website
119 Q2Q B2B Finance & Accounting Visit Website
120 o11 B2B Finance & Accounting The AI Agent Inside Every App Visit Website
121 Wideframe B2B Marketing AI agent for video work outside the NLE Visit Website
122 Reframe B2B Marketing AI agents to automate hardware procurement Visit Website
123 Sitefire B2B Marketing Marketing suite for the agentic web Visit Website
124 Sequence Markets FinTech Payments Smarter and faster trade execution for digital assets Visit Website
125 ZeroSettle FinTech Payments Avoid the 30% App Store Tax by Supporting Direct Billing in your App Visit Website
126 Grade FinTech Payments Payroll for performance Visit Website
127 Forum FinTech Payments The first regulated exchange to trade on attention. Visit Website
128 Terranox AI Industrial Energy AI-powered uranium exploration Visit Website
129 Condor Energy Industrial Energy Energy OS enabling reliable, cheap and sustainable electricity supply. Visit Website
130 Lexius B2B Security AI Security Guards Visit Website
131 Hex Security B2B Security Agentic Offensive Security at Scale Visit Website
132 Protent B2B Security Protent turns passive surveillance into proactive intelligence. Visit Website
133 BeeSafe AI B2B Security Stopping Scams Before They Reach Your Customers Visit Website
134 CatchBack Cards Consumer Gaming a platform for maximizing the thrill of collecting trading cards Visit Website
135 Mantis Biotechnology Consumer Gaming Physics-Enhanced Datasets for Low-Resource Machine Learning Visit Website
136 CodeWisp Consumer Gaming Anyone can create real games with AI Visit Website
137 Pax Historia Consumer Gaming The first AI-powered grand strategy platform Visit Website
138 Corvera B2B Operations AI agents for CPG brands Visit Website
139 MochaCare B2B Operations AI-Supercharged Humans for Home Care Agency Growt Visit Website
140 EigenPal B2B Operations AI Document Workflows for Enterprises Visit Website
141 Pollen B2B Operations AI Agents for Customer Success Visit Website
142 Galactic Resource Utilization Space Industrials Aviation & Space Building the First Hotel on the Moon Visit Website
143 Beyond Reach Labs Industrials Aviation & Space Space solar arrays that grow to the size of a football field in orbit Visit Website
144 AxionOrbital Space Industrials Aviation & Space Foundation models for 24/7 Earth Observation Visit Website
145 Sila B2B Productivity Agent & Team Communication Workspace Visit Website
146 Unisson B2B Productivity The AI product specialist for customer-facing teams Visit Website
147 Emdash B2B Productivity Open-source Agentic Development Environment Visit Website
148 Cofia B2B Productivity AI automations that write themselves Visit Website
149 Robby B2B Productivity Agentic revenue growth for home service businesses. Visit Website
150 Approxima B2B Analytics One package to take your mobile app to production. Visit Website
151 Laurence B2B Analytics RL for performance marketing Visit Website
152 Constellation Space B2B Analytics AI for space mission assurance. Visit Website
153 Proximitty FinTech Credit & Lending Autonomous loan servicing and collections Visit Website
154 Squid Industrials Energy AI-powered grid planning in your browser Visit Website
155 RoboDock Industrials Energy Robots that run autonomous depots for autonomous fleets. Visit Website
156 Voxel Energy Industrials Energy Energy independent data centers with solar and repurposed batteri… Visit Website
157 Return Signals B2B Retail AI luxury concierge for E-commerce brands Visit Website
158 General Legal B2B Legal The AI native law firm for growth stage companies Visit Website
159 AutoSitu B2B Legal AI-native workspace for municipal development review Visit Website
160 Vector Legal B2B Legal AI Law Firm + Legal Tech Platform for Startups Visit Website
161 Wayco B2B Legal AI operator for legal case referrals Visit Website
162 Fed10 B2B Legal AI agents that replace your policy consultants Visit Website
163 LegalOS B2B Legal The AI-powered law firm for complex work visas Visit Website
164 Arcline B2B Legal Startup legal work handled by elite lawyers & same-day turnaround Visit Website
165 Fort Consumer Electronics Strength Tracking Wearable Visit Website
166 Doomersion Consumer Electronics Doomscroll to learn languages Visit Website
167 Pocket Consumer Electronics The world’s best AI note-taking device and app Visit Website
168 Ashr B2B Human Resources Mimic Users in Your Production Environment to Catch Agent Fails Visit Website
169 Skillsync B2B Human Resources Find anyone in open source Visit Website
170 Resonate Consumer The first AI-native messaging platform. Visit Website
171 Origami Robotic Industrials Manipulate Anything Robot Visit Website
172 Hlabs Industrials Making an industrial supply chain for building robots in the USA Visit Website
173 Congruent Industrials We build radars for end-to-end autonomy Visit Website
174 DAIVIN Industrials Tankless Dive Gear – Breath Autonomy at Sea, Land & Space Visit Website
175 ARC Prize Foundation Industrials AI benchmarks that measure general intelligence and inspire new id… Visit Website
176 OctaPulse Industrials Climate Robotics and computer vision to automate fish farming from hatche… Visit Website
177 Maywood FinTech Banking & Exchange AI for M&A Visit Website
178 Verdex FinTech Insurance Satellite Imagery Verification for Insurance Visit Website
179 Caretta B2B Sales Realtime AI for Sales Calls Visit Website
180 SpotPay FinTech: Consumer Finance Cross-border Personal Finance on Stablecoins Visit Website
181 GrazeMate Industrials Agriculture Robot Cowboys that Herd Cattle with AI Drones Visit Website
182 Voltair Industrials Drone Self Charging Drones Visit Website
183 DroneTector Industrials Drone Technology to detect and track hostile drones Visit Website

You might also be interested in checking out some of the best Startup deals offered by YC Startup School.